At least four people were killed and 63 injured after a Metro-North passenger train derailed on a sharp curve in the Bronx borough of New York City on Sunday morning, officials said.

Eleven people were in critical condition at area hospitals, according to New York Governor Andrew Cuomo, although he said he believed they were in stable condition. Three of the dead were ejected from the train. Several people had to be extracted from the wreckage.

"Obviously a very tragic situation," said Cuomo, who declined to speculate on the cause of the crash. "The first order of business is to care for the people on the train."

Cuomo said that the train's operator had survived the crash and was being treated for unspecified injuries.

FDNY Chief of Department Edward Kilduff said that airbags and jacks were used to stabilize the cars and remove victims. Some of those injured had to be cut out of the damaged train cars.

"The train is pretty beat up, it flipped to some degree," said Kilduff. "There was a lot of personal belongings thrown around."

The seven-car Hudson Line commuter train was headed toward Grand Central Station when it derailed near the Spuyten Duyvil Station in the Bronx on a long curved section of the track at around 7:30 a.m., according to Metro-North.

President Barack Obama says his thoughts and prayers are with the friends and families of the victims of the fatal train derailment in New York City.

The White House issued a statement saying the president was briefed on the accident Sunday morning.

The White House says Obama will continue to stay in touch with New York officials throughout the day.

At least two of the cars had flipped on their side after the crash, and one car stopped only feet from the banks of the Harlem River. Cuomo told reporters that the four fatalities were from the two cars that had flipped on their side.

The locomotive car could be seen lying on its side near the train tracks.

A senior State Department official told ABC News there was no indication that the crash was a result of terrorism or criminal conduct. The National Transportation Safety Board announced they would be sending a team to investigate the derailment.

Metro-North announced that rail service was indefinitely suspended between the Croton Harmon and Grand Central stations in New York. Amtrak service to upstate New York was also suspended.

People concerned they knew a passenger on the train were instructed to call 311, if you live outside of New York you can call 212-NEW-YORK.